Acupuncture & Electro-Therapeutics Research
Editor: Yoshiaki Omura
Volume 48, 2023
ISSN: 0360-1293; E-ISSN: 2167-9010
4 numbers per volume
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Aims & Scope
The aim of the journal is to provide an international forum for the exchange of ideas and promotion of basic and clinical research in acupuncture, electro-therapeutics, and related fields. The journal was established in order to make acupuncture and electro-therapeutics a universally acceptable branch of medicine through multidisciplinary research based on scientific disciplines. The final goal is to provide a better understanding of both the beneficial and adverse effects of these treatments in order to supplement or improve existing methods of diagnosis, prognosis, treatment, and prevention of diseases in both Western and Oriental medicine.
The journal will accept original basic or clinical research papers, worthwhile reviews on safe and effective therapeutic methods, applications, limitations, theories, or principles of acupuncture and electro-therapeutics, including electro-analgesia or any method of treatment through the application of various types of electric or electromagnetic field stimuli as well as electrical and nonelectrical diagnostic methods. The journal will also consider serious research on any related methods of treatment such as Shiastsu, moxibustion, herbal medicine, and standard and experimental stages of Western medicine, with physiological and pharmacological studies. We accept clinical, experimental, and theoretical studies, particularly on the early diagnosis and safe and effective treatment of intractable medical problems, such as intractable pain, dystonia, Parkinson’s disease, Alzheimer’s disease, cancer, and cardiovascular disease. In general, submitted papers must be based either on the documentation of data through scientifically proven or accepted methods, or on the explanation of new theories in the field with critical evaluation of such ideas. For example, papers may present data such as the effects of acupuncture on the cardiovascular or nervous systems using blood chemistry, hemodynamics, enzymes, and other biochemical or pathophysiological, Bi-Digital O-Ring Test, nerve conduction velocity, threshold stimulation for pain, somatosensory evoked potentials or any other electro-physiological method that is scientifically acceptable. Papers not dealing directly with acupuncture, electro-therapeutics, or the related methods of diagnosis or treatment mentioned above will also be considered if they have important implications for either improving diagnostic methods or treatment, or elucidating the underlying principles or the history or medicolegal aspects of these fields.
Editor-in-Chief & Founder
Yoshiaki Omura, M.D., Sc.D., F.A.C.A., F.I.C.A.E., F.A.A.I.M., F.R.S.M., D.A.B.F., A.B.F.M.
Mailing address: 800 Riverside Drive, New York, NY 10032, USA
Phone (212) 781-6262, Fax (212) 923-2279
President, International College of Acupuncture & Electro-Therapeutics; Director of Medical Research, Heart Disease Foundation; Adjunct Professor, Dept. of Community & Preventive Medicine, New York Medical College; Professor, Dept. of Non-Orthodox Medicine, Ukrainian National Medical University; Executive Board Member & Chairman of the Eastern Medicine Advisory Board of the American Association of Integrative Medicine (A.A.I.M.); Former Visiting Research Professor, Dept. of Electrical Engineering, Manhattan College, New York, NY, USA; Former Adjunct Professor, Dept. of Pharmacology, Chicago Medical School, North Chicago, IL, USA; Former Visiting Professor, Dept. of Psycho-physiology, University of Paris, Paris, France
Motomu Ohki, M.Sc (Applied Chemistry, Tokyo University), F.I.C.A.E. (Honor) &
Kamila Paluch, M.S. (Bioengineering, Columbia University
Main Editor Representing China
Haifa Qiao, MD, MM
Dean and Distinguished Professor, College of Acupuncture, Shaanxi University of Chinese Medicine, Xixian Area, Shaanxi, China
Andersson, Sven, M.D., Ph.D., F.I.C.A.E., Prof. of Neurophysiology, Dept. of Physiology, Univ. of Goteborg, Gotborg, Sweden
Araujo, M. Sanchez, M.D., F.I.C.A.E., Pres., Latin Ameri-can Societies (FLASMA), & Integral Health & Therapeutics Research Inst. (INSIT), Caracas, Venezuela
Atsumi, Kazuhiko, M.D., Ph.D., F.I.C.A.E., former Dir.and Prof. Institute of Medical Electronics, Univ. of Tokyo, Hongo Bankyo-Ku, Tokyo, Japan
Becker, Robert O., M.D., F.I.C.A.E., Consultant Biomed.Science, former Prof. Orthopedic Surgery, Upstate Med. Ctr., Starroute, Lowville, NY, USA
Beyens, Francais, M.D., F.I.C.A.E., Ex-President, Belgian Assoc. of Med. Acupuncturists, Bruxelles, Belgium
Borrmann, Robert, Ph.D., F.I.C.A.E., Prof./former Chairman, Dept. of Electrical Engineering, Manhattan College, Bronx, NY, USA
Cao, Xiao-Ding, M.D., F.I.C.A.E., Prof./Chairwoman, Dept. of Acupuncture Analgesia and former Dean of Basic Med. Science, Shanghai Med. Univ. Shanghai, PRC
Ceccherelli, Francesco, M.D., F.I.C.A.E., Research Professor, Institute of Anesthesiology and Reanimation and Regulatory Center on Complementary Medicine, University of Padova, Via C. Battisti, 267-35121 Padova, Italy
Chang, Hsiang-Tung, Ph.D., F.I.C.A.E., Prof./Director, Shanghai Brain Research Institute Academia Sinica 319, Yo-Yang Road, Shanghai, PRC
Chen, Gong-Bai, M.D., Sc.D., F.I.C.A.E, former Prof. of Neurosurgery and Ex-President of Inst. of Neurology and of Hua Shan Hospital, Shanghai Med. Univ., PRC
Chen, Yemeng, C.M.D., L.A.C., F.I.C.A.E., Academic Dean, New York College of Traditional Chinese Medicine, Mineola, NY, USA
Chun, Sae-il, M.D., F.I.C.A.E., Prof & Director, Rehabilitation Hospital, Yonsei University, College of Medicine, Seoul, Korea
Cohen, Marc, M.B.B.S. (Hons.), Ph.D., BmedSc (Hons.), F.A.M.A.S., DipAC, F.I.C.A.E., Head of Dept. of Complementary Medicine, RMIT University, Bundoora, Victoria, Australia
Crul, Jan, M.D., F.I.C.A.E., Prof./Chairman, Dept. of Anesthesiology, Radabout Zickehuls Katholic Univ., Nijmegen, The Netherlands
Cyong, J., M.D., Ph.D., F.I.C.A.E., Chairman of Lab. Immunopharmacology, Oriental Med. Res. Ctr. of the Kitasato Inst., Tokyo, Japan
de Smul, Andre, M.D., F.I.C.A.E., Prof., Dept. of Surgery, Pain Clinic, Akademisch Ziekenhuis, Vrije Univ., Brussels, Belgium
Doenicke, Alfred, M.D., F.I.C.A.E., Prof./Director of the Institute for Anesthesiology, Polyclinic, Munich Univ., Munich, Germany
Farber, Paulo L., M.D., F.I.C.A.E., Director/Coordinator, Acupuncture Research Dept., Div. Obstetrics & Gynecology, Univ. of Sao Paulo Med. School, Sao Paulo, Brazil
Floter, Thomas, M.D., F.I.C.A.E., President, Schmerz Therapeutisches Kolloquium Pain Treatment Ctr., Frankfurt Main, Germany
Genazzani, Andrea R., M.D., F.I.C.A.E., Pres., Intl. Soc. of Gynecological Endocrinology, E.I.C. Gynecological Endocrinology, Prof. Inst. of Obstetrics & Gynecology, Univ. of Modena, Modena, Italy
Giron, Giampiero, P., M.D., F.I.C.A.E., Prof. and Director, Instituto Di Anesthesiologia E Rianimazione, and Regulatory Center on Complementary Medicine, University of Padova, Via C. Battisti, 267-35121 Padova, Italy
Gleditsch, Jochen, M.D., F.I.C.A.E., former Pres., German Physicians Acupuncture Assoc., Munchen 2, Germany
Greenfield, William, D.D.S., F.I.C.A.E., Prof./Assoc. Dean for Hospital and Extramural Affairs, New York Univ. Dental Ctr., New York, NY, USA
Gunn, C. Chan, M.A., A.B., M.C., Chir., F.I.C.A.E., Prof., University of Washington, Seattle, WA, USA & Gunn Pain Clinic, Vancouver, BC, Canada
Hayhoe, Simon, B.S., M.B., M.R.C.S., I.C.R.P., F.I.C.A.E., Ex-Chairman & Treasurer, ICMA, British Med. Acupuncture Society, Dept. of Anesthetics, Essex County Hosp., Colchester, UK
Hegyi, Gabriella, M.D., Ph.D., M.Sc., Head of Dept of CAM, Pecs University, Health Science Faculty, Hungary
Hisamitsu, Tadashi, M.D., Ph.D., F.I.C.A.E., Prof./Chairman, Dept. of Physiology, School of Med., Showa Univ., Shinagawa-ku, Tokyo, Japan
Hui, S. C., M.D., F.I.C.A.E., former Pres., Western Australian Med. Acupuncture Society, Nedlands, Western Australia
Iliev, Emil, M.D., F.I.C.A.E., Chairman, Bulgarian Society of Traditional Chinese Med., Sofia, Bulgaria
Jojima, Takashi, M.D., F.I.C.A.E., former Pres., Brazilian Med. Acupuncture Assoc., Ave. Paes de Rarros, Sao Paulo, Brazil
Junnila, Seppo, M.D., F.I.C.A.E., Pres., Finnish Med. Acupuncture Soc. and Mgr. of Salo District Health Care Center, Salo, Finland
Kaada, Birger, M.D., Ph.D., F.I.C.A.E., Prof. of Neurophysiology, Lab. of Clinical Neurophysiology, Rogaland Central Hospital, Stavanger, Norway
Kim, Ki Ho, M.D., F.I.C.A.E., F.A.A.P.M.R., Director, Kim Institute of Rehabilitation Medicine, Livingston, NJ, USA
Klaus, Wolfgang, M.D., Ph.D., F.I.C.A.E., Prof. and Chairman, Dept. of Pharmacology, Univ. of Cologne, Cologne, Germany
Lee, Matthew, M.D., M.P.H., F.I.C.A.E., Prof./Dir. of Rehabilitation Med., Goldwater Memorial Hospital, New York Univ. Med. Center, and Pres., American Academy of Acupuncture, New York, NY, USA
Lisenyuk, Victor, M.D., Sc.D., F.I.C.A.E., Prof./Chairman, Dept. of Non-Orthodox Med., Ukrainian National Med. Univ., Kiev, Ukraine
Lu, Dominic P., D.D.S., Ph.D., F.I.C.A.E., Prof of Oral Medicine, Univ. of Pennsylvania; Director of Medical and Dental Externship Education and Chief of Special Care Dentistry, Lehigh Valley Hospital
Lundberg, Thomas, NI.D., Ph.D., F.I.C.A.E., Assoc. Prof., Dept. of Physiology II, Karolinska Inst., Stockholm, Sweden
Mamtani, Ravi, M.D., F.I.C.A.E., Prof. of Clinical Preventive Med., Dir. of Med. Acupuncture Program, New York Med. College, Valhalla, NY, USA
Marcus, Paul, M.D., former Chairman, British Med. Acupuncture Soc., Admin., Newton House, Warrington, Cheshire, England
Maric-Oehler, Walburg, M.D., F.I.C.A.E., Pres. German Med. Acupuncture Assoc., Bad Homburg, Germany
Mayroher, Otto, M.D., Dr. N.C. Mult., F.I.C.A.E., Prof. and Chairman, Inst. of Anesthesiology, Univ. of Vienna, Austria
Melzack, Ronald, Ph.D., F.I.C.A.E., Prof. of Psychology, McGill Univ., Montreal, Canada
Muteki, Gousuke, M.D., Ph.D., F.I.C.A.E., Prof. Emeritus & Former Chairman, Dept. of Anesthesiology & Dir. of Emergency Intensive Care Unit, Kurume Univ., Kurume, Fukuoka, Japan
Nappi, Giuseppe, M.D., F.I.C.A.E., E.I.C., Functiona Neurology, Prof. & Dir., 1st. Neurologic Ctr. Mondino, Univ. of Pavia, Pavia, Italy
Negro, Francesco E., M.D., F.I.C.A.E., Pres., 4th World Congress of Scientific Acupuncture of ICMART 90, Pres. of the Italian Acupuncture Soc., Rome, Italy
Needham, Joseph, F.R.S., F.A.B., F.I.C.A.E., Sometime Master of Gonville and Caius College and Dir., East Asian History of Sci. Library, Cambridge Univ., UK
NG, Lorenz, M.D., F.I.C.A.E., former Chairman of Intra-Mural Res. Lab., Natl. Inst. on Drug Abuse, Rockville, MD, USA
Niboyet, J., M.D., Sc.D., F.I.C.A.E., President of Mediterranean Acupuncture Assoc., Marseilles, France
Nissel, H., M.D., F.I.C.A.E., Pres., Austrian Soc. of Acupuncture & Auricular Medicine, Ludwig Boltzmann Acupuncture Inst., Vienna, Austria
Nogier, Paul., M.D., F.I.C.A.E., Pres. Groupe Lyonnais d’Etudes Medicales, E.I.C., Auriculo-Medecine, Lyon, France
Nordenstrom, Bjorn E. W., M.D., F.I.C.A.E., former Chairman, Nobel Committee, Karolinska Inst., Stockholm, Prof. Emeritus of Diagnostic Radiology, Karolinska Inst., Stockholm, Sweden
Orkin, Louis, M.D., F.I.C.A.E., former Prof./former Chairman, Dept. of Anesthesiology, Albert Einstein College of Medicine, Bronx, NY, USA
Otsuka, Yasuo, M.D., Ph.D., F.I.C.A.E., Dir. Oriental Med., Inst. Kampo Med., Dept., Kitasato Univ., 5-9-1 Shirokane, Minato-ku, Tokyo, Japan
Peng, Alfred, M.D,, F.I.C.A.E., former Pres. NY Society of Acupuncture for Physicians & Dentists, St Luke’s Hospital, New York, NY, USA
Pontinen, P. J., M.D., F.I.C.A.E., Pres. Nordic Med. Acupuncture Soc. and Assoc. Prof. of Anesthesiology, Univ. of Kuopio, Finland
Procacci, Paolo, M.D., F.I.C.A.E., Prof. Univ. degli Studi di Firenze, Cattedra de Terapia Medica Sistematica, Viale G.B. Firenze, Italy
Qiao, Haifa, M.D., Shaanxi University of Chinese Medicine College of Acupuncture, China
Rabischong, Pierre, M.D., F.I.C.A.E., Prof./Chairman of Dept. of Anatomy and Dean of the Faculty of Med., Univ. of Montpellier, Dir. of Biomechanics, Res. Unit of INSERM at Montpellier, Montpellier, France
Redfearn, Edward, B.A., M.B.B., Chir. (Camb) DRCOG, F.I.C.A.E, Ex-Chairman, British Med. Acupuncture Soc., Birmingham, England
Samosyuk, Ivan A., M.D., Sc.D., F.I.C.A.E., Prof., Dept. of Neuropathology & Reflexotherapy, Kiev State Inst. for Post Graduate Studies of Physicians, Doragozhitskaya St. Kiev, Ukraine
Schnorrenberger, Claus C., M.D., F.I.C.A.E., Past Pres. of German Physicians Acupuncture Assoc., Frieburg, Germany
Shibutani, Kinichi, M.D., Ph.D., F.I.C.A.E., Prof. Anesthesiology & Dir. of Pain Clinic, Westchester County Med. Ctr., New York Medical College, Valhalla, NY, USA
Skokijev, Antonije, M.D., Sc.D., F.I.C.A.E., Pres. of the Yugoslavian Med. Acupuncture Society and Prof. and Dir of Clinic for Maxillo-Facial Surgery, Military Med. Academy, Belgrade, Yugoslavia
Soulairac, Andre, M.D., Sc.D., F.I.C.A.E., Prof. and Chairman, Dept. of Psycho-Physiology, Faculty of Sci., Univ. of Paris VI, Paris, France
Spiegel, Edward, D.D.S., F.I.C.A.E., Former Chairman, CME Courses of American Academy of Head, Neck and Facial Pain, Erie, PA
Studer, Elizabeth, M.D., F.I.C.A.E., Pres. Med. Acupuncture Soc. of Switzerland, Lugond, Switzerland
Takeshige, Chifuyu, M.D., Ph.D., F.I.C.A.E., Prof. Emeritus and former Dean of Physiology Dept., School of Med., Showa Univ., Shinagawa-ku, Tokyo, Japan
Tobler, Paul, M.D., F.I.C.A.E., Dozent for General Med., Univ. of Zurich & Univ. of Bern Zurich, Switzerland
Travell, Janet, M.D., F.I.C.A.E., Emeritus Clinical Prof. of Med., George Washington Univ., Washington, DC, USA
Trachtenberg, Alan I., M.D., M.P.H., Medical Officer, N.I.H. on Drug Abuse, 6120 Executive Blvd., Suite 450, Rockville, MD 20892, USA
Tsuchiya, Mitsuharu, M.D., F.I.C.A.E., President of the Federation of Portugese Acupuncture & Moxibusion Av. Colegio Militar, 20 A-r/c. DT-Loja-1500 Lisboa, Portugal
Xuetai, Wang, M.D., F.I.C.A.E., Prof./Vice Dir., Expert Comm. of China, Academy of Traditional Chinese Med., Former President of China Acupuncture & Moxibustion Society, Bejing, China
Yamamura, Hideo, M.D,. H.D., F.I.C.A.E., Prof Emeritus, former Chairman, Dept. of Anesthesiology; former Dean, School of Med. Tokyo Univ.; Pres., All Japan Acupuncture Society Tokyo, Japan
Alfred L. Copley, M.D., Dr. Med.h.c. (Heidelberg Univ.) F.I.C.A.E. (deceased)
Beckman, Sandra, M.A. (Speech Pathology), M.A. (Educational Computer Science), Campus Coordinator for Distance Learning in Communicative Disorders, Dept. of Human Services, Western Carolina University, Cullowhee, North Carolina, USA; Former Adjunct Assistant Prof., Dept. of Communication Disorders & Sciences, Adelphi University, Manhattan Center
Camp, Virginia, M.D., F.I.C.A.E., Wycombe General Hosp., High Wycombe Bucks, England
Glennie-Smith, Keith, M.B., B.S., F.F.A.R.C.S., F.I.C.A.E., Consultant Anesthesist, Dept. of Anesthesiology, Poole General Hosp., Dorset, England
Grant, Alan, M.B., F.I.C.A.E., c/o Prof. Andre Soulairac, Dept. of Psychophysiology, Faculty of Science, Univ. of Paris VI, France
Jungck, Dietrich, M.D., F.I.C.A.E., Vice-Pres., Schmerz-Theraputisches Kolloquium, Clinic for Pain Treatement, 2000 Hamburg I, Germany
Merrick, Pipsisewa, M.Sc., Ph.D., Dept. of Biology, Univ. of North Carolina, NC, USA
Nakajima, Hiroaki, M.D., Ph.D., Dir. of Pulmonary Div. & Assoc. Prof., Dept. of Med., School of Med., Showa Univ., Tokyo, Japan
Nihrane, Abdallah, Ph.D., F.IC.A.E. Visiting Associate Prof. Integrative Medicine, ICAET, Adjunct Associate Prof., Microbiology, New York City College of Technology, CUNY, New York, Former Assistant Prof., Dept. of Medicine, Mount Sinai School of Medicine, New York, Former Visiting Scientist, NIH, NIAID, Bethesda, MD, USA
Omura, Alexander K., M.D., Dir., Dept. of Anesthesiology, Benefis Hosp., 4631 Fox Farm Road, Great Falls, MT, USA
Shimotsuura, Tasuhiro, M.D., F.I.C.A.E., Exec. Secretary, Japan Bi-Digital O-Ring Test Assoc., Dir., Dept. of Med., St. Maria Hospital, Kurume, Fukuoka, Japan
Sola, Anders, M.D., F.I.C.A.E., Assoc. Prof., Dept. of Anesthesiology, School of Med., Univ. of Washington, Seattle, WA, USA (former Pain Specialist, U.S. Air Force)
ORCID iD: Authors are required to provide their ORCID iD. Papers without an ORCID iD will not be accepted for submission.
Authors are requested to submit the original manuscript (and revised manuscript if needed) electronically via email to email@example.com. The manuscript, including text, figures, tables and figure legends, should be prepared in Microsoft Word format. Articles should be single-spaced and pages should be numbered consecutively, centered at the bottom of each page.
Please view this sample of an article published in Acupuncture & Electro-Therapeutics Research, Volume 45, #1, pp. 3-14 before sending in your submission: https://www.ingentaconnect.com/contentone/cog/aetr/2020/00000045/00000001/art00002
The paper should have the following sections:
1. Title of Article
2. Names of authors with academic degrees followed by institutional affiliation
3. Contact information of person to contact (name, academic degree, address, telephone #, fax #, and email)
4. Tentative date of manuscript received by editor’s office and tentative date of acceptance in parentheses
5. Abstract (preferably less than 250 words)
6. Keywords (6 pertinent keywords)
8. Materials & Methods
Every paper must have this basic format. Any paper without experimental or clinical research setup shown by good schematic diagrams or actual photographs with captions that are easy to understand and that provide information about how the research was carried out will not be accepted. Materials & Methods should have enough information to reproduce the research by other scientists. For these materials and methods, if electrical or electromagnetic field stimulation is used, they should provide electrical parameters as well as electromagnetic field parameters and wave forms of the stimulating electrical pulses or electromagnetic field pulses.
After suggested revisions for improvement, once the paper is going to be officially accepted for publication, please adhere to the guidelines below:
Include a cover letter, and insert “Acupuncture & Electro-Therapeutics Research Submission” in the subject line of the email. The cover letter should contain the name, address, telephone #, fax # and email address of the author responsible for correspondence. Follow the General Manuscript Form guidelines below to prepare the manuscript, figures, and tables.
When the manuscript is accepted for publication, the author(s) will be required to provide a high-resolution PDF file. Manuscripts are accepted for consideration with the understanding that they have not been published elsewhere except in abstract form and are not concurrently under review elsewhere. Material accepted for publication will not be released publicly prior to its appearance in the journal.
General Manuscript Form: Papers should be typed in English with at least 3-cm (1 1/8 in.) margins on paper approximately 22 × 28 cm (8 1/2 × 11 in.) in size. Please consult the most recent issue of the journal for style and format. Number all pages consecutively, beginning with the title page. Use metric units of measure; other units may be given in parentheses. Typically, only three levels of headings are recognized. The paper should be organized as follows:
Title Page: First, before the title of the article, leave a 2-inch margin from the top of the page (for publisher reference information). The title should be brief and specific. The title page should contain in the following order: title (centered in bold, size 14, font Times New Roman), a space, the name(s), academic degree(s) (in bold) and affiliation(s) of author(s) including city, state, postal code, and country should appear (not in bold, centered in size 12 font Times New Roman). Following this, each co-author should be listed in the same way with a space between each author. Also indicate the author to whom correspondence should be addressed, with complete mailing address, telephone #,
fax # and e-mail address. Please include “Date Received” (approximate date the manuscript is to arrive at the editorial office) & “Date Accepted” (approximately 3 months after the date received) in parentheses. These dates will be tentative and subject to change. Leave an empty space before the abstract.
Abstract: The subtitle “ABSTRACT:” should be bold and written starting in the left margin. An abstract of 300 words or less should follow below (as a separate line) and be lined up with the colon from “ABSTRACT:”. It should contain a concise summary of the methods, results, conclusions, and other significant points. Any unfamiliar abbreviated word should not be used without giving corresponding original word in parenthesis.
Key Words: For the purpose of proper covering of indexing periodicals, provide 6-8 key words immediately following the abstract, with a space in between, and margins lined up with the text of the abstract. Use a semi-colon in between the key words and the first letter of each key word should be capitalized.
Text: Arrange the text with main headings of Introduction, Materials and Methods, Results, Discussion, list of Conclusions, Acknowledgments (and source of funding), References, Tables, and Figures. Pages should always reach full margins. Place figures/tables as close to the text reference as possible, however they can be moved to the next page in order to avoid a page being too short. Use generic names of drugs. Give name, City, State, and Country of the manufacturer of any chemicals, equipment or software mentioned in the text. Define all nonstandard abbreviations the first time they appear in the text.
References/Reference List: Within the text references should be cited with sequential numbers in parentheses. The reference list should be numbered sequentially by order of appearance in the text. Follow the style samples given below. Journal citations in the reference list should contain the following: (a) surnames and initials of all authors (surnames precede initials); (b) title of article; (c) journal title should not be abbreviated; (d) volume, inclusive pages and year. Journal’s name and Book’s title should be underlined.
1. Omura, Y., Pathophysiology of acupuncture treatment: Effects of Acupuncture on Cardiovascular and Nervous systems. Acupuncture & Electro-Therapeutics Research,
The International Journal. Vol 1, pp. 55-141, 1975.
1. Sambrook, J.; Fritsch, E. F.; Maniatis, T. Molecular cloning: A laboratory manual,
2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 1989.
Chapter in Edited Book:
1. Den Otter, E.; Dullens Hub, F. J.; Van Govern, H.; Pels, E. Antitumor effects of macrophages injected into animals: A review. In: MacBride, J. K.; Stuart, A., eds.
The macrophage and cancer. Edinburgh: Econoprint; 1987:119–141.
Tables: Tables should be numbered and cited sequentially in the text. Avoid very wide or long tables that would not fit a printed page. Each table should have a title, and each column in the table should have a brief heading. Define all abbreviations in the table footnote at the bottom of the table. (Text within tables and figures should be font size 12; font size smaller than 11 will not be accepted.)
Figures: Figures should be numbered and cited sequentially in the text. Use figures/photos which are high-quality. Avoid light lettering and shading that will not reproduce well. Complex formulas should be prepared as illustrations. Care must be taken that letters and other symbols do not become so small that they are illegible when the figure is reduced (by 25%). All figures/photos will be printed in black & white unless otherwise noted by author. The author is required to bear the costs for the publication of color figures. An “Author Option” form will be provided upon acceptance for open access, color figures and offprint options. If no color will be used for the final print of the publication, there will be no cost to the author; as long as the figures are in black & white, the publisher will not charge any fees even if there are many figures (more than 10). However, please make sure that if there are more than 2 curves in a figure, you are able to differentiate between the 2 without color.
Figure Legends: The figure legend should be as clear as possible and should fully describe the contents of the figure. If the figure is from a previously published article, indicate that permission has been obtained from the original publisher. Center figure legend under figures.
Permissions: If data from any other source is used in tables or figures it is the responsibility of the author(s) to obtain permission to reproduce such material. Provide proof that permission has been granted from the original publisher and indicate the source.
Final Accepted Manuscript/Disk: The final manuscript file must be submitted to the Editorial office in a high-resolution pdf file. Ensure that the hard copy and electronic file match exactly.
Copyright: Publications are copyrighted for the protection of the authors and the publisher. A Transfer of Copyright Agreement will be sent to the author whose manuscript is accepted for publication. This form must be completed and returned to the Editor before the article can be published. Although every effort is made by the publisher and editorial board to see that no inaccurate or misleading data, opinion, or statement appears in this Journal, they wish to make it clear that the data and opinions appearing in the articles and advertisments herein are the sole responsibility of the contributor or advertiser concerned. Accordingly, the publisher, the editorial board, editors, and their respective employees, officers, and agents accept no responsibility or liability whatsoever for the consequences of any such inaccurate or misleading data, opinion, or statement.
Author Options: Articles appearing in Acupuncture & Electro-therapeutics Research are available to be open access and also contain color figures (not a condition for publication). Authors will be provided with an Author Option Form, which indicates the following options. The form must be completed and returned with the final manuscript file(s) even if the answer is “No” to the options. This form serves as confirmation of your choice for the options.
A Voluntary Submission Fee of $125.00 includes one free page of color and a 50% discount on additional color pages (color is discounted to $50.00 per color page).
Open Access is available for a fee of $200.00. Color would be discounted to $50.00 per color page.
The use of Color Figures in articles is an important feature. Your article may contain figures that should be printed in color. Color figures are available for a cost of $100.00 per color page. This amount would be discounted to $50.00 per color page if choosing to pay the voluntary submission fee or the open access option as indicated above.
If you choose any of the above options, a form will be sent with the amount due based on your selection, at proof stage. This form will need to be completed and returned with payment information and any corrections to the proof, prior to publication.
Online Fast Track Publication: Accepted manuscripts will be loaded to Fast Track with DOI links online. Fast Track is an early e-pub system whereby subscribers to the journal can start reading and citing the articles prior to their inclusion in a journal issue. Please note that articles published in Fast Track are not the final print publication with proofs. Once the accepted manuscript is ready to publish in an issue of the journal, the corresponding author will receive a proof from our Production Department for approval. Once approved and published, the Fast Track version of the manuscript is deleted and replaced with the final published article. Online Fast Track publication ensures that the accepted manuscripts can be read and cited as quickly as possible.
Acupuncture & Electro-therapeutics Research (ACUP) Peer Review Policy
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Access Current Articles (Volume 48, Number 2)
Table of Contents:
Volume 48, Number 2
Catgut Implantation at Acupoints has an Immunosuppressive Effect on Autoimmune Uveitis by Reducing Th1/Th17 Lymphocytes – 77
Feifei Chen, M.D.,* Jianying Zhao, M.D.,† Shuyang Zhong, M.D.,† Fengming Zheng, M.D.,‡ and Xiaobo Hao, M.D.†
*Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China
†First Hospital Affiliated to Guangxi University of Traditional Chinese Medicine, Nanning, China
‡Chinese Medicine Hospital Shangyu Shaoxing, Shangyu, Shaoxing, Zhejiang, China
Catgut implantation at acupoints (CIA) has been applied as medical treatment for autoimmune diseases. Yet, its effect and mechanism of this therapy on autoimmune uveitis is still unknown. Here we aimed to explore the immunoregulatory effect of CIA in the experimental autoimmune uveitis (EAU) rat model. Lewis rats were induced with EAU by injecting IRBP1177–1191 peptide, and subsequently treated with CIA. In the CIA group, delayed mild inflammation was observed with alleviated infiltration of lymphocytes and ocular damage. Flow cytometry showed significant decrease in Th17 lymphocytes at Day 9, 13, and 18 post-immunizations (P<0.05) after CIA. The Th1 lymphocytes were also significantly decreased at Day 13 and 18 post-immunizations (P<0.05) in the CIA group. IL-17 and IFN-γ mRNA levels were notably decreased at Day 9, 13 and 18 post-immunizations (P<0.05) after CIA. Serum IL-17 and IFN-γ levels in the CIA group were significantly decreased at Day 9, 13 and 18 post-immunizations (P<0.05). Ocular inflammation was markedly inhibited after catgut implantation at Pishu (BL20) and Shenshu (BL23) acupoints in the EAU-induced rats. In summary, this study revealed that CIA could reduce Th1 and Th17 lymphocytes and the expression of IFN-γ and IL-17 in the EAU rat model, suggesting its potential in uveitis treatment. Key words: Catgut implantation; Experimental autoimmune uveitis; Th17 lymphocytes; Th1 lymphocytes; BL20 acupoints; BL23 acupoints
Retrospective Analysis of Acupuncture Combined with Warm Acupuncture in the Treatment of Constipation with Defecation Disorder – 93
Yi-Tan Che, Physician,* Hui-xie Zhao, Physician,† and Tian-Qi Wang, PhD‡
*Department of Acupuncture and Moxibustion, Beijing Daxing Teaching Hospital, Capital Medical University, Beijing, China 102600
†Department of Vascular, Shijiazhuang Hospital of Traditional Chinese Medicine, Hebei, China 050000
‡Lecturer, School of Traditional Chinese Medicine, Capital Medical University, Beijing, China 100069
Background: To compare the clinical efficacy of acupuncture combined with warm acupuncture and moxibustion and conventional acupuncture in the treatment of constipation with defecation disorder. Methods: By retrospective analysis, 60 patients with constipation with defecation disorder admitted to the Department of Acupuncture and Moxibustion in Daxing Hospital, Capital Medical University from January 2020 to March 2022 were selected. According to whether the treatment was combined with warm acupuncture therapy, 60 patients were divided into two groups, conventional acupuncture group and acupuncture combined with warm acupuncture group, with 30 cases in each group. The conventional acupuncture group was given conventional acupuncture treatment, and the acupoints were selected as follows: ① Abdomen: Zhongwan, Qihai, Guanyuan, Tianshu (Shuang), abdominal knot (Shuang); ② Limbs: branch groove (double), Zusanli (double), Juxu (double), Taichong (double); ③ Waist and back: Pishu (double), Danshu (double), middle (double), lower (double), needle 30min, 1 time a day. Each course was treated for 5 days with a rest for 2 days, and a total of 4 courses were treated. On the basis of the treatment in the conventional acupuncture group, warm acupuncture and moxibustion therapy was performed on the middle and lower scales (Shuang) at 1d, 3d and 5d of each course. Wexner scale and PAC-QOL scale were used to compare the constipation symptom score, quality of life score, and total constipation symptom and quality of life in the two groups after treatment were lower than those before treatment (P < 0.05), and the scores in the acupuncture combined with warm acupuncture group were more ideal than those in the conventional acupuncture group (P < 0.05). After treatment, both groups achieved certain clinical efficacy, and the acupuncture combined with warm acupuncture group was better than the conventional acupuncture group (P < 0.05). Conclusion: Acupuncture combined with warm acupuncture is better than conventional acupuncture in the improvement of constipation symptoms, quality of life and effective rate.
Key words: Defecation disorder type constipation; Warm acupuncture; Acupuncture; Retrospective analysis
Dry Needling and Neurodevelopmental Therapy versus Neurodevelopmental Therapy Alone on Spasticity and Functions in Patients with Stroke: A Randomized Controlled Trial – 103
Kubra Kucuktepe, MSc, PT* and Gozde Iyigun, PhD, PT†
*Cyprus Science University Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Kyrenia, North Cyprus via Mersin 10, Turkey
†Eastern Mediterranean University Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Famagusta, North Cyprus via Mersin 10, Turkey
Background: Dry needling is suggested as a novel and promising method for treating spasticity and functions after stroke. Objectives: To understand the effects of dry needling and neurodevelopmental therapy (NDT) compared to NDT alone on post-stroke spasticity and functions. Materials and Methods: Forty-two patients with post-stroke spasticity were randomized into two groups: NDT and dry needling (n=21) or NDT alone (n=21). Dry needling was applied over the study group’s gastrocnemius, quadriceps femoris, flexor carpi radialis, and biceps brachii muscles. The Modified Ashworth Scale and range of movement (ROM) assessment were used to assess spasticity before treatment (T1), immediately after the 1st session (T2), and after the 12thsession (T3), while Nine Hole Peg Test (NHPT), 10-Meter Walk Test (10MWT), and Fullerton Advanced Balance (FAB) Scale were used to assess functions at T1 and T3. Results: Dry needling and NDT were more effective in improving the gastrocnemius muscle tone (χ2 =9.31; p=.025) than NDT alone. Compared to NDT alone group the improvement was higher on all ROM measurements in the dry needling and NDT group, which was more remarkable at T2 than T3. The dry needling and NDT group exhibited more significant improvements in the upper extremity (NHPT; F=88.316, p<.001, η2=.694), lower extremity (10 MWT; F=7.075, p=.011, η2=.495), and balance (FAB; F=58.435, p<.001, η2=.600) functions compared to the NDT alone group. Conclusion: Dry needling and NDT effectively reduce spasticity but only significantly in the gastrocnemius muscle. Dry needling and NDT is also more effective than NDT alone in improving upper and lower limb and balance functions in stroke patients. Trial Registration: The trial was registered to ClinicalTrials.gov (identifier: NCT03863678) on March 5, 2019.
Key words: Dry needling, Neurodevelopmental Therapy, Spasticity, Upper Extremity Functions, Lower Extremity Functions, Balance
Two Cases Report of Acupuncture Treatment at the Acupoint BL1 (Jingming) of Both Eyes in Treating Traumatic Trochlear Nerve Palsy – 119
Chun-Feng Su, M.D.*† Ching-Huang Lin, PH.D.‡ and Qiao Fan PH.D.§
*Department of Ophthalmology, Universal Eye Center, Tainan, Taiwan
†Graduate School of Engineering Science and Technology, National Yunlin University of Science and Technology, Yunlin, Taiwan
‡Department of Electronic Engineering, National Yunlin University of Science and Technology, Taiwan
§Center for Quantitative Medicine, Duke-NUS Medical School, National University of Singapore, Singapore
Purpose: To explore a safe and effective therapy in treating diplopia due to traumatic trochlear nerve palsy. Subjects: Two cases of traumatic trochlear nerve palsy both induced by motorcycle traffic accidents were presented in this study. Both cases were right superior oblique muscle palsy after an accidental head injury affected for more than 6 months (case 1) and 4 years (case 2). Methods of treatment: Both cases were subjected to acupuncture therapy at the acupoint BL1 (Jingming) of both eyes using disposable stainless steel acupuncture needles and were clinically evaluated by the ophthalmologist after each session. Each session extended to 20 minutes, 2 or 3 sessions per week till fully recovered. Result: Clinical symptoms of both cases were significantly improved after 3 sessions and continued the treatment for two more months to consolidate the curative effect due to fear of recurrence of symptoms. Conclusion: Acupuncture can be considered an effective therapy in the treatment of diplopia due to traumatic trochlear nerve palsy in addition to conservative therapy.
Key words: Acupuncture; Acupoint BL1 (Jingming); Traumatic trochlear nerve palsy; Superior oblique muscle palsy; Case report
An Integrative Approach, by Using a Bi-Digital O-Ring Test (BDORT), Advanced Bioinformatics, and Clinical Testing for the Development of New Effective Treatment of Infections Caused by Human Papillomaviruses (HPV) – 133
Momir Dunjic, MD, Ph.D., F.I.C.A.E., Cert MD-ORT (4Dan),* Stefano Turini, MBioLSc, Ph.D.,† Slavisa Stanisic MD, Ph.D., FICAE., Cert MD-ORT,‡ Nenad Sulovic, MD, Ph.D.,§ Sasa Cvetkovic, MD, Ph.D.,¶ Dejan Mihajlovic, MD,# Katarina Dunjic, MD,** Dusan Simic, MD,†† Marija Dunjic, MD,‡‡ and Leonida Vitkovic, MD, Ph.D.§§
*Ass Prof of Ob/Gyn & Integrative Medicine University of Priština in Kosovska Mitrovica, Faculty of Medicine., Faculty of Pharmacy, Novi Sad, Faculty of Health Science, AMEUECM Maribor, President of Serbian Association of Integrative Medicine, President Serbian Acupuncture Section of Serbian Medical Society, Serbia – Slovenia
†Senior Lecturer in Biochemistry and Microbiology, School of Physiotherapy, AMEU-ECM University, Maribor, Koper, Project Manager UNIQUE Treatments, Main Researcher at BDORT Center of Functional Supplementation and Integrative Medicine, Belgrade, Serbia,Italy-Slovenia-Serbia
‡Ob/Gyn, University of Priština in Kosovska Mitrovica, Faculty of Medicine, Serbia, Faculty of Pharmacy, Novi Sad, Serbia, Alma Mater Europaea (AMEU-ECM); Maribor, Slovenia, Serbia-Slovenia
§Prof of Ob/Gyn, University of Priština in Kosovska Mitrovica, Faculty of Medicine, Serbia
¶Ass Prof. of Ob/Gyn, University of Priština in Kosovska Mitrovica, Faculty of Medicine, Serbia
#University of Priština in Kosovska Mitrovica, Faculty of Medicine, Serbia
**BDORT Center for Functional supplementation and Integrative Procedures, PhD Student, School of Medicine, University of Belgrade, Serbia
††Department of Ob/Gyn, Health Center, Nis, Serbia
‡‡Puls Cardiologic Center, Belgrade, Serbia
§§Prof of Hystology, University of Priština in Kosovska Mitrovica, Faculty of Medicine, Serbia
Introduction: HPV is a family of double-stranded DNA viruses that infect the mucous epithelium. Most of these infections regress without consequences; however, the high-risk HPV viral strains can determine a tumor transformation of the epithelium, giving rise to tumor forms such as cervical cancer. The analysis mostly applied to define abnormalities of the membranes is the PAP test and the treatment is reconciled, in most cases through prevention. Alongside the standard protocol, we have determined that a blend of essential oils has an effect in determining the negativization of HPV. Materials and Methods: We made use of the BDORT technique in order to determine the specific percentages of each component of the prepared oil blend. To confirm this, two advanced Molecular Docking software have been applied (Swiss Dock and 1-Click Docking). The mixture of oils was subsequently applied, in the form of vaginal capsules, on a group of HPV (+) positive patients, who were tested for the presence of a virus, before and after treatment, by RT-PCR, Colposcopy, and BDORT to evaluate the state of epithelium before and after the assumption of oil vaginal capsules. Results: The mixture of oils has produced the negativization of HPV, determined by BDORT and confirmed by RT-PCR, in the treated patients. Discussion: We have determined that the blend of essential oils, prepared here, influenced the negativization of the virus, in all the patients treated. Conclusions: The operative efficacy of these oils in the negativization of HPV has been demonstrated.
Key words: HPV-16; Oncoprotein E6; Major Capsid Protein L1; Apigenin; Celery; BDORT, Bioinformatics
The Integrative Approach in the Diagnosis and Treatment of Patients, With Anxiety-Depressive Conditions, by Using Bidigital O-Ring Test (BDORT) and Advanced Informatics and Artificial Intelligence (AI) Tools, With a Pure Beam of Radio Waves, in the Opposi– 153
Dr. Prof. Stefano Turini MBioLSc Ph. D.,* Assoc. Prof. Dr. Momir Dunjic,MD, Ph. D., F.I.C.A.E., Cert MD-ORT (4 Dan),† Prof. Dejan Krstic, Ph.D.,‡ Prof. Dr. Slavisa Stanisic MD, Ph.D., FICAE., Cert MD-ORT,§ Prof. Dr. Nenad Sulovic,MD, Ph.D.,¶ Ass. Prof. Dr. Sasa Cvetkovic,MD, Ph.D.,¶ Marija Dunjic, MD,# and Katarina Dunjic, MD**
*Senior Lecturer in Biochemistry and Microbiology, School of Physiotherapy, AMEU-ECM Maribor, Koper, Slovenia Project Manager and Main Researcher UNIQUE TREATMENTS DOO-Belgrade and BDORT Center for Functional supplementation and Integrative Procedures, Italy-Slovenia-Serbia
†Ob/Gyn & Integrative Medicine, University of Priština in Kosovska Mitrovica, Faculty of Medicine., Faculty of Pharmacy, Novi Sad, Faculty of Health Science, AMEU-ECM Maribor, President of Serbian Association of Integrative Medicine, President Serbian Acupuncture Section of Serbian Medical Society, Member of Board of European Society of Integrative Medicine, Serbia – Slovenia
‡Faculty of Occupational Safety, University of Nis, Serbia
§Ob/Gyn, University of Priština in Kosovska Mitrovica, Faculty of Medicine, Serbia, Faculty of Pharmacy, Novi Sad, Serbia, Alma Mater Europaea (AMEU-ECM); Maribor, Slovenia, Serbia-Slovenia
¶Ob/Gyn, University of Priština in Kosovska Mitrovica, Faculty of Medicine, Serbia
#Puls Cardiologic Center, Belgrade, Serbia
**BDORT Center for Functional supplementation and Integrative Procedures, PhD Student, School ofMedicine, University of Belgrade, Serbia
Introduction: Organisms are constantly immersed in an ocean of electromagnetic waves which cause different effects on the body. At the end of 1980, it was determined that the frequency of 6.66 Hz is responsible for anxiety-depressive states and that all subjects who manifest such disturbances vibrate on this frequency. Materials and Methods: The BDORT technique was applied to evaluate parameters associated with the subject’s status (Sirtuin-1, TERT, TP-53, Zoloft, Thromboxane B2, Acetylcholine, DMAE, Thymus Gland). Furthermore, the GAP-7 and HAMD psycho-aptitude tests were applied to evaluate the subject’s anxiety-depressive level. At the end of the evaluation, the subject was treated with the OPFT (Opposite Phase Frequency Treatment), i.e., with the counter-phase frequency of -6.66 Hz, in order to cancel the 6.66 Hz frequency. The treatment was performed by listening, with headphones, to the specific anti-frequency, elaborated thanks to the combined use of artificial intelligence software. Results: Patients treated with the OPFT showed an increase, measured by BDORT, of specific biological parameters and a decrease in Thromboxane B2, in accordance with expectations, due to the balance between the sympathetic and parasympathetic systems. The data obtained, on the specific parameters, showed a statistically significant correlation (r < 0.005 ** and r < 0.001 ***). Discussion: The increase in the value of parameters Acetylcholine and the decrease in Thromboxane B2, was the basis of the alleviation of anxiety-depressive symptoms. As a corollary of them, there was an increase in parameters such as Sirtuin-1, TERT, and TP-53. Conclusions: The OPFT technique proved to be effective in reducing anxiety depressive symptoms in all treated subjects.
Key words: ELF; Opposite-phase Frequencies; 6.66 Hz, -6.66 Hz; Radiofrequency Therapy; BDORT, Anxiety, Depression
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